Most of the time when you want to treat a disease, symptoms such as nausea and vomiting are attacked to help the patient not to get worse. These symptoms, at the same time, are involved in a large number of diseases associated with both the digestive system and others. systems of the body, and it really tends to be quite unpleasant and harmful to health to keep these symptoms present, since it could cause the patient to lose weight, which in the presence of a disease only subtracts points from the immune system and the body's resistance.
In conclusion, everything becomes a chain that at the end only brings a very dark scenario for the patient's life. This is when Cannabidiol, a non-psychoactive compound that is effective in treating most of the symptoms of many diseases, makes its appearance. , but will this cannabinoid be able to alleviate both nausea and vomiting? Will science be able to demonstrate its effectiveness? And how could this scientific advance help us? These are some of the questions that we will answer below.
In general: Nausea and vomiting
First of all, we need to discuss some concepts of global interest, to answer the questions, and that is that, before vomiting, nausea will always be present, the latter is nothing more than a rather unpleasant and compelling sensation of vomiting, which can be present in a patient without the need for vomiting at any time and is usually located in the throat or epigastrium. Vomiting is the powerful expulsion of gastrointestinal contents through the mouth, due to indeliberate contractions of the abdominal and thoracic muscles.
These symptoms are quite common, and can be accompanied by both simple general discomfort and quite serious pathologies, this makes both pharmacological and natural medications quite broad and effective. The causes will depend on the agent that is causing the condition and are extremely numerous, but the most common are pregnancy, uremia, alcoholism, postnasal drip, postgastrectomy vomiting or increased intracranial pressure.
Studies involving Cannabis compounds as a treatment for nausea and vomiting
During the study stage, still in force, of cannabis compounds such as CBD, applied in different, mostly chronic diseases, an interaction of certain cannabinoids with the attenuation of symptoms such as nausea and vomiting has been observed. Below, we mention some :
In a 5-day double-blind, placebo-controlled study, patients receiving chemotherapy treatment, half of them were given a placebo, and the other half, before starting chemotherapy treatment, were given a placebo. medicine made from cannabis compounds such as THC, called dronabinol.
On the remaining days they were dosed with Ondacetron, placebos and Dronabinol or Ondacetron and Dronabinol. At the end of the study, the effectiveness of THC could be compared with that of Ondacetron alone, in the treatment of these late emetic symptoms, which in an evaluation of the The percentage of absence of nausea was observed, with Ondacetron reducing nausea by 64% and the placebo only by 15%, while the THC-based medication reduced it by 74%.
An investigation carried out on several clinical trials involving patients with nausea and vomiting and the administration of cannabinoids such as THC, showed that patients who received less THC during the studies had more symptoms, while those who were administered The cannabinoid considerably reduced the gag reflex and therefore vomiting.
A latest study published in the journal Pediatrics demonstrated that medical marijuana is effective on seizures and nausea resulting from chemotherapy in pediatric patients. A meta-analysis was performed based on 22 previously conducted studies on this interaction in children and adolescents.
The conclusion was that THC proved to be highly effective for the treatment of nausea and vomiting in younger patients, however, CBD or cannabidiol had only demonstrated its effectiveness in the treatment of seizures.
The effectiveness of THC on the endocannabinoid system has been investigated to reduce nausea and vomiting, where it has been associated with an action of this compound on the CB1 receptor, which can regulate these symptoms like other pharmacological medications. There is no evidence that CBD attenuate these symptoms, and that the combination of THC with a conventional medication increases the antiemetic results.
With this we can conclude. . .
According to research, CBD continues to be an excellent option in the treatment of various diseases, but in the case of symptoms such as nausea and vomiting, the ideal is the use of THC, the difference between these compounds is the ability of THC to be psychoactive on the patient, while CBD does not cause the same effect.
Studies have also objected to the use of inhaled cannabis compounds, this being one of the most common ways of consuming by many patients, both recreationally and for purely medicinal benefits.
There are some THC-based medications used to treat nausea and vomiting, more than anything aimed at patients undergoing chemotherapy treatment, which has been yielding great results and a better way to carry out cancer treatment for these patients.
However, we always recommend interacting with the treating doctor and asking him any questions or discomforts that arise with the use of this compound, in addition to evaluating the possibilities of administering the compound, treating the side effects, and making a small observation about what What the patient should or should not take into account if it is their first time using THC.
The use of THC must be highly controlled by a professional, so we avoid falling into aggravations or incorrect doses of the compound. Let us remember that it is a cannabinoid that can produce psychoactivity, which is why it is usually more delicate when used.