Cannabidiol or CBD continues to demonstrate that its use as a therapeutic measure or treatment for various ailments and diseases, is going further and further, this time it shows us how its use in the treatment of Alzheimer's, one of the most common dementia diseases today, constituting up to 65% of registered cases, is showing optimal results and satisfaction for both science and the patient.
When looking for medications for the treatment of Alzheimer's, we will find a long list of specialized drugs to treat stop this mental degeneration produced by the disease, but currently CBD comes to help these patients obtain more pleasant results and thus be able to optimize their quality of life.
In this article we talk a little about the direct treatment with CBD for Alzheimer's, its role in the body, the benefits that its use could provide us both preventively and in the treatment of Alzheimer's as such and more.
What does science think?
To begin, it is good to highlight the opinion of the most experts, since in this way we can know the support that the implementation of this exogenous cannabinoid has on the treatment of Alzheimer's.
The Spanish doctor Mariano García de Palau is one of the professionals who supports the information about this treatment. He has been dedicating his work for 15 years to the study of the use of CBD in the treatment of diseases such as Alzheimer's. He currently works at Kalapa clinic where he works. role as a CBD researcher, carrying out clinical work with patients and collaborating with various institutions.
In 2011, a group of American scientists carried out a study with CBD in animals, specifically mice with Alzheimer's, where the results obtained demonstrated that cannabidiol or CBD was useful in promoting the development of neurons or neurogenesis, which in turn decreases decomposition of cognitive functions.
This, as can be seen, showed that CBD could be a treatment that promises high-quality results, being key in the adequate treatment of the disease.
Another study was carried out in 2016 which consisted of gathering a small group of 10 patients to observe the results of using CBD in approximately 4 weeks. After its completion it was concluded that the results were once again as desired and even exceeded expectations, as they caused a fairly satisfactory decrease in the neuropsychiatric inventory score from 44,3 to 12,9.
Translating it as a decrease in aggression, delirium, agitation, apathy and irritability, at the same time having a high impact on research, it was taken to a second level by conducting a much more extensive study, thus solidifying the bases for its use. of cannabidiol on Alzheimer's.
Just like these studies, there are many others that have been carried out successfully and that have shown that The anti-inflammatory and antioxidant response that cannabidiol or CBD has on the body allows the delay in the appearance of symptoms in dementia disease.This is because the neuroinflammation and oxidative stress that occur in Alzheimer's could cause neurotoxicity and neuronal death in the medium and long term without the effectiveness of cannabinoids.
Why use CBD in the treatment of Alzheimer's?
The answer is simple, the use of CBD in the treatment of Alzheimer's has demonstrated its high effectiveness in developing good results, helping natural endocannabinoid receptors to fulfill functions such as activating certain receptors and reducing the appearance of neurological diseases such as Alzheimer's.
An example would be the improvement that external cannabinoids can cause in behavioral problems such as appetite or the deterioration of sleep patterns in Alzheimer's.
As if that were not enough, CBD compared to other medications, has the advantage of offering the body a wide range of effects that constitute Alzheimer's disease, taking into account that many of these other medications only have one function.
One of the most important reasons for using CBD as a treatment for Alzheimer's is the stimulation of neuronal growth or neurogenesis, since these patients quickly suffer damage to the neuronal tissue causing serious neurological effects such as loss of appetite, personality changes, memory loss, among others.
In fact, this idea of implementing different mechanisms to reach the same objective is well recognized among health professionals and in turn is part of their intention when primarily treating other diseases or medical conditions.
How does Cannabidiol act in the body to treat Alzheimer's?
The studies carried out on Alzheimer's focus on a direct relationship between endocannabinoids and the disease, so thanks to this the possibility of using external cannabinoids to help delay has been highlighted. the negative effects of Alzheimer's.
Cannabidiol or CBD, thanks to its anti-inflammatory function, directly helps reduce inflammation in those areas of the brain that are affected by the disease, thus considerably reducing the progression of Alzheimer's, since this localized inflammation in the brain cells is responsible for the incorrect functioning of the brain.
Another important function of CBD in the body is ability to act as an antioxidant against the oxidative process which also commonly occurs in degenerative processes of the brain, causing little oxygen in the cells and therefore the gradual degeneration of the brain in the face of Alzheimer's disease.
In 2011, a study was carried out where the effectiveness of CBD on inflation and reduction of oxidation was verified by an independent mechanism; it acts on a receptor such as PPAR or receptor-γ activated by the proliferated peroxisomes.
By acting on this receptor, cannabidiol was able to reduce inflammation and the production of oxygen species to protect brain cells. In turn, it was capable of producing neurogenesis.
Protection against beta-amyloid is another of the functions that CBD has within the body to counteract the disease, maintaining neuroprotection and preventing the accumulation of plaques; as well as the inhibition by THC of the enzyme acetylcholinesterase, which is responsible for the breakdown of acetylcholine, a neurotransmitter responsible for the processes of memory formation and restoration.
In short, cannabinoids such as THC and CBD function as a brain stabilizer in the presence of Alzheimer's or even before it, that is, as a pre-treatment, regulating its energetic functions and maintaining its functionality; Therefore, CBD will stabilize cognitive functions of the brain, which are clearly affected during the illness, especially appetite.
What would be the appropriate dose of CBD for the treatment of Alzheimer's?
Each body is different and the way in which CBD will take effect will depend on many factors in the body, among these you can find the level of Alzheimer's disease, the tolerance you have to the cannabinoid, the weight, circulation problem, the response to ingesting CBD especially in people who have never consumed the component and of course the quality of the product.
Based on titration, which was the term used in the book “CBD: A Patient's Guide To Medical Cannabis” by Leonard Leinow and Juliana Birnbaum” to refer to the correct way to administer the medication, we have that the best method is escalation, which consists of starting with a low dose or microdose and increasing it in relation to the effect that the medication has on Alzheimer's disease.
So, it allows us to carry out a gradual survey on the effect of CBD on our body and thus allows us to establish a correctly adapted daily dose.
When talking about microdoses, it refers to the administration of 0,5 to 20mg of CBD per day, however, it is recommended that the microdose used for Alzheimer's be 1 drop of 500mg of CBD. About our CBD oil, taking into account that 1 drop of 500mg of CBD oil contains 2mg, subsequently increase the dose until the desired requirement is achieved.
You can also consult more extensively our article on dosage and use of CBD where we more correctly detail the dosage in milligrams and in drops of oil according to its concentration.
Benefits of CBD treatment for Alzheimer's.
As has been seen, CBD is playing a very important role in the therapeutic resolution of diseases such as Alzheimer's, therefore, we have that the benefits for the patient are quite optimal, on this occasion we break down each of the advantages that we grants CBD treatment for Alzheimer's:
- Promotes neurogenesis or neuron growth
- Reduces or prevents inflammation of brain cells
- Produces neuroprotection against the accumulation of plaques due to beta-amyloid
- Inhibits acetylcholinesterase, reducing cognitive damage
- Reduces damage caused by oxidative stress in brain cells
- Helps proper circulation by increasing blood flow to the brain
- It considerably helps eliminate the symptoms of dementia.
Many patients with Alzheimer's usually present symptoms of anxiety, so CBD also has anxiolytic characteristics to suppress or reduce these aggregates of the disease.
Consult your trusted doctor!
It is important that Consult your doctor's opinion on the use of CBD As a treatment for Alzheimer's, this will allow you to have a more direct professional opinion, in turn, which could help you establish a correct dosage, based on the body's reaction to the gradual administration of CBD.
It is likely that the doctor will add other treatments to complement and maximize the desired optimal result on the disease, in turn monitoring the evolution of the disease and taking care of adverse reactions or unnecessary excessive intakes of the medication.
Ask them for recommendations on the correct use of the medication and where to buy it, discuss the pros and cons of this process, and discuss your Alzheimer's treatment decision with them.
Final analysis on CBD treatment for Alzheimer's.
Thanks to all this information, we can conclude by saying that CBD treatment for the therapeutic care of Alzheimer's is totally reliable, although there are still small details that continue to be studied, the results obtained to date are totally satisfactory.
Used from preventive treatment to treatment of the disease, cannabidiol has had a good impact on a scientific and personal level, since it provides the patient with the ease of consuming a medicine that fulfills multiple functions, helping them treat the problems of Alzheimer's and promoting a quality of life much better than expected.
In 2006, a study was published in Molecular Pharmaceutics in which a group of researchers from the University of Connecticut reported that cannabis could be considerably the best option to eliminate the abnormal grouping of malformed proteins, which is a hallmark of Alzheimer's disease. They themselves assured that Treatment with cannabinoids would be the new medicinal revolution in the future, and currently we are not far aways of reality.
The main objective of cannabidiol is to reduce or slow down the effects caused by Alzheimer's disease, so seeing the results will require some patience, you will be able to notice the difference as soon as CBD performs its function by reducing inflammation.
Although the effects of using cannabinoids are short-term, with time and research it is expected to reach these long-term effects, at the moment CBD does not leave its users dissatisfied, offering desired results and a good support your body in the face of illness.
I would like to know if to treat Alzheimer's, after the fifth week you stop using it or continue with the same drops. I would like to go to a doctor but I am from Peru and I don't think I will find one here who recommends its use or who is familiar with this.