There are various treatments that are responsible for controlling Parkinson's disease, since, as it is an incurable disease, the treatments are basically focused on slow down the disease, encompassing everything from medications to lifestyles designed specifically for this type of patient, CBD currently and for several years has been included in the world of medications suitable for the treatment of this disease.
In the case of Parkinson's disease, CBD has proven to be of great help, significantly controlling the side effects of the disease and improving the lifestyle of patients on a large scale; In this article we will talk a little about Parkinson's, its direct relationship with CBD and we will break down information that allows us to recognize CBD as a treatment for the disease.
Parkinson's and its role as a neurodegenerative disease
Parkinson's disease over the years has made it very clear what its function is in the body, attacking the nervous system. gradually degeneratingMore specifically, this disease attacks areas of the brain specifically responsible for the body's motor functions, thus causing the famous tremor at rest, as well as sensory problems, rigidity and in the most serious cases, dementia.
Parkinson's disease causes death of neurons which are found in the substantia nigra of the brain, where the neurotransmitter called dopamine is produced, which is responsible for maintaining the proper transport of signals sent by the brain.
These data are extremely important to know the role of CBD in Parkinson's diseasen, which we will develop little by little.
It is worth mentioning that this condition is the second most common neurodegenerative disease worldwide, it occurs more in men than in women and especially in elderly people, specifically 60 years of age and older, however, there is a small group of minors. 40 years old who are affected by Parkinson's, which is called juvenile.
CBD studies that described its action on Parkinson's
Studies carried out with CBD date back more than 200 years, even Parkinson's disease was treated by doctors in ancient times with cannabis indica tincture, helping patients reduce side effects, such as the famous tremors, and in turn regulate their sleep problems, allowing them to have a more effective conciliation.
The big difference between that time and this is that those doctors did not know the process by which CBD could help treat this disease, despite that they only continued using it as an option; Today we have the advantage of both technological and scientific advances, allowing new studies and obtaining more concrete answers about these results.
Various studies have been carried out using inhaled cannabis as a method, which in the vast majority of cases have had good results in terms of improving the symptoms of the disease.
One of them was the one carried out 5 patients who suffered from Parkinson's, in order to reduce tremors, administering cannabis in the form of cigarettes along with the antiparkinsonian treatment of the patients, after long hours the researchers concluded that, cannabis, thanks to its sedative and anxiolytic effects, decreases and in most sometimes eliminates tremor.
The most recent study that demonstrated a very interesting result was the one carried out in Brazil on 21 patients diagnosed with Parkinson's disease. It consisted of the administration of high and low doses of CBD in tablets, a third of which was distributed in placebos, the first group was dosed with 300mg/day of CBD orally for 6 weeks, the second was administered doses of 75mg/day also for 6 weeks and the third and final group was given the placebo for the same time.
This showed as a result a notable improvement in the symptoms of the disease of the patients who received the highest dose of the drug, the rest of the groups had little relevant results. Concluding that CBD maintains an optimal quality of life in patients, helping them cope with the symptoms of the disease, however, they mention that several more studies are needed to give cannabidiol a more solid basis.
Advantages of CBD in Parkinson's disease
Although the research is still not sufficient and often contradicts each other, we have been able to capture some benefits or advantages that cannabidiol offers in the treatment of Parkinson's.
Anti-inflammatory advantageSince this disease is a degeneration of neurons located in the area of the substantia nigra, affecting in turn the production of dopamine and norepinephrine, it causes damage that can simultaneously produce certain neuronal inflammation, which would trigger or accelerate the symptoms. in the patient.
This inflammation may have a direct relationship with the disease, or it may only be a side effect. It is not yet known exactly. However, what is known is that this inflammation only increasingly worsens neuronal degeneration and therefore the patient severity level.
Thanks to CBD contains anti-inflammatory properties mediated by the receptors of the endocannabinoid system, this cannabis compound could considerably reduce this problem, thus helping the patient to improve.
Another advantage or benefit of CBD consumption in Parkinson's, is linked to its neuroinflammation-reducing effect, which in turn, according to studies, is directly related to depression, so By using cannabidiol we could prevent or eliminate depression in a patient with Parkinson's.
One of the most common side effects and trigger of other conditions in patients with Parkinson's are sleep problems, patients who suffer from insomnia, this is consequently the cause of other effects of the disease, such as cramps that They interrupt sleep in the middle of the night, involuntary movements while sleeping, dyskinesias, hallucinations and even the side effects of some medications.
One of the characteristics of CBD or cannabidiol is its mild sedative effect, which would completely improve the patient's sleep, scientifically proven according to studies, in addition to providing the body with rest so that it can carry out all its self-healing processes, which normally occur at night when we sleep.
Oxidative stress is one of the causes of Parkinson's disease that produces neuronal damage, which is quite worrying in the development of the disease. This oxidation of neuronal cells is what causes, through a specific process, the death of the cell and therefore the decrease in dopamine production.
The antioxidant function of CBD It could significantly help prevent this oxidation and in turn affect the production of dopamine, this will allow the patient to maintain a much more optimal lifestyle.
Likewise, according to previous studies, CBD has shown to have properties to improve dopamine production, acting through receptors called GPR6 found in the same area where dopamine is produced.
In this study it was noted that two receptors called GPR3 and GPR6 are members of a family of receptors coupled to G proteins, knowing that GPR3 is related to Alzheimer's and GPR6 is related to Parkinson's disease and taking into account that are involved with endocannabinoids and phytocannabinoids, cannabidiol was effective in significantly decreasing the recruitment of certain proteins, thus functioning as an inverse agonist at the GPR3 and GPR6 receptors.
This important discovery could be the definitive answer we need about CBD as an effective treatment for Parkinson's, so proper research and results are awaited to discuss this possibility.
How should you use CBD in Parkinson's?
As we have already seen, cannabidiol could provide certain advantages in Parkinson's disease, being more effective for some people than for others, so when using this cannabis compound we must be clear that its use is linked to the symptoms or side effects of the disease, and that treating it could greatly help us cope with the problem.
When the patient feels that the symptoms are getting worse, the CBD could help you reduce them, take into account its function as a sleep regulator to prevent certain sleep disorders, as well as in the case of patients with psychosis or dementia.
Regarding the correct dosage, what is normally recommended in the use of CBD is to start with minimum doses and go gradually increasingHowever, as we have seen in the studies, the patients who have had excellent results are patients who have been administered high doses of the cannabinoid, so it is recommended to use the same gradual or escalating dose to know the needs. of your body in relation to the disease until you reach this high dose.
Below is a table with some dosage recommendations by weight and dose intensity:
Weight (kg) | Dose (low – medium – high) |
50 | 10 – 30 – 60 mg |
60 | 13 – 38 – 75 mg |
70 | 15 – 45 – 90 mg |
80 | 17 – 72 – 105 mg |
90 | 20 – 60 – 120 mg |
100 | 22 – 67 – 135 mg |
110 | 25 – 75 – 150 mg |
Let's learn about Larry's experience with CBD to combat Parkinson's
Larry Smith, a former police captain, who has experienced Parkinson's disease for more than 20 years without obtaining a comforting result from his medications, Larry specifically must take 20 pills daily, which apart from being tedious, They cause certain effects that do not allow you to lead a good quality of life.
Larry tells us his story and tells us that, after spending years under medical treatments without obtaining the results he wanted, even undergoing brain surgeries which were very expensive, he and his wife, exhausted by the situation, decided to try medicinal cannabis, In their goal of never giving up, they traveled together from South Dakota to San Diego, California, a place where medical cannabis was not illegal.
To their satisfaction, after so much searching to improve their lives, they both discovered the great benefits of medicinal cannabis, now Larry Smith has a treatment with cannabis drops. About our CBD oil which considerably improves the side effects of the disease, as well as dyskinesia; In a short interview that was carried out, you can see Larry completely uncontrolled with the involuntary movements that the disease produces, as he directs the drops to his mouth, it is only a matter of 4 minutes to observe a completely different Larry, a former captain who can speak without any problem, without involuntary movements, even his hands were firm.
Summarizing CBD and Parkinson's
Concluding the topic we can say that, mainly, CBD or cannabidiol continues to be a cannabis compound that can help many living beings counteract a great variety of diseases and perhaps in some cases not directly or not to all, but in the vast majority, the power of the properties of this cannabinoid continues to provide satisfaction.
As we were able to observe, the studies on CBD as a treatment for Parkinson's are still very deficient and new and much more research is needed to understand and provide the necessary information about this interaction. So far, great progress has been made and it is expected that, In the not too distant future, research will confirm the effectiveness of CBD in this disease.
However, there are many cases of people who maintain CBD treatment for Parkinson's and it has helped them on a large scale; although the disease there is no cure, CBD is working in the same way as conventional medications, trying to slow down the progress of the disease, treating symptoms multiple times and with a broad spectrum, helping to reduce symptoms such as dyskinesia, dementia, serving as a neuroprotectant and helping to prevent the decrease in dopamine.
Additionally, it is worth mentioning that if you plan to use cannabidiol for the treatment of Parkinson's, it would be best consult with a doctor, since he will be in charge of evaluating your condition, level of aggravation and will indicate other treatments that, in complement with CBD, can help you restore your vine qualitya.
From specific diets to dosages, it will be the advice that the doctor will give you, as well as the examination of your body to know if you tolerate CBD, if you do not have adverse reactions and if you have doubts, it is also the best option.
Finally, we recommend that you pay attention to the advances of this great cannabis compound and its relationship as a treatment for Parkinson's disease.